Role of cell free microRNA-19a and microRNA-19b in gestational diabetes mellitus patients
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چکیده
منابع مشابه
MicroRNA-19a and microRNA-19b promote the malignancy of clear cell renal cell carcinoma through targeting the tumor suppressor RhoB
Clear cell renal cell carcinoma (ccRCC) is the most common subtype of renal cell carcinoma, which shows high aggressiveness and lacks biomarkers. RhoB acts as a tumor suppressor that inhibits the progression of ccRCC. In the present study, we examined the effects of oncogenic microRNAs, miR-19a and miR-19b, on RhoB expression in ccRCC cells. The results showed that both miR-19a and miR-19b coul...
متن کاملHealth Education in Gestational Diabetes Mellitus and Quality of Life
Background & aim: Incidence rate of gestational diabetes mellitus (GDM) has been estimated to be 18.5%. GDM is associated with various challenges in terms of care and public health. The present study aimed to investigate the effects of health education and behavioral interventions on the quality of life in the patients diagnosed with gestational diabetes mellitus (GDM). Methods: This randomized...
متن کاملGestational diabetes mellitus
Introduction: Gestational diabetes mellitus (GDM) is defined as any degree of glucose intolerance with onset or first recognition during pregnancy. The prevalence range from 1 to 14% of all pregnancies, depending on the population studied and the diagnostic tests employed. Risk assessment for GDM should be undertaken at the prenatal visit. Women with clinical characteristics of GDM should und...
متن کاملRole of Adipokines and Other Inflammatory Mediators in Gestational Diabetes Mellitus and Previous Gestational Diabetes Mellitus
Previous Gestational Diabetes Mellitus (pGDM) is a common condition and has been associated with future development of Type 2 Diabetes Mellitus (T2DM) and Metabolic Syndrome (MS) in women affected. The pathogenesis and risk factors implicated in the development of these conditions later in the lives of women with pGDM are not as yet fully understood. Research has recently focused on a group of ...
متن کاملA MicroRNA Signature in Gestational Diabetes Mellitus Associated with Risk of Macrosomia.
BACKGROUND/AIMS MicroRNA (miRNA) is a small non-coding RNA molecule that functions in regulation of gene expression by targeting mRNA to affect its stability and/or translation. The aim of this study was to evaluate the miRNAs involvement in gestational diabetes mellitus (GDM), a well known risk factor for fetal overgrowth. METHODS Differential microRNA expression in placental tissues of norm...
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ژورنال
عنوان ژورنال: 3 Biotech
سال: 2019
ISSN: 2190-572X,2190-5738
DOI: 10.1007/s13205-019-1952-9